Researchers

Patrick T. Fueger, PhD

Patrick T. Fueger, PhD

Assistant Professor
Departments of Pediatrics and Cellular & Integrative Physiology
Indiana University School of Medicine
635 Barnhill Drive
MS 2049
Indianapolis, IN 46202
Phone:
Fax:
Email:
(317) 274-7862
(317) 274-4107
pfueger@iupui.edu

Research Program Membership

Islet Function & Survival

Research Description

The goals of Dr. Fueger’s laboratory are to identify and characterize novel molecular regulators of functional beta cell mass in vitro and extrapolate this work to the in vivo setting. This laboratory is particularly interested in two molecules sharing similarities, and yet key differences – Mig6 and Ack1. Mig6 and Ack1 both contain domains that negatively regulate tyrosine kinases, and Ack1 also functions as a tyrosine kinase. Current projects are directed towards identifying novel beta cell growth factors and molecular brakes for proliferation, elucidating their signaling pathways, and translating these discoveries into animal transplantation and/or beta cell expansion models.

Publications

http://www.ncbi.nlm.nih.gov/pubmed?term=fueger%20p

Education

PhDVanderbilt University, Nashville, TN, 2004
Postdoctoral FellowshipDuke University, Sarah W. Stedman Nutrition and Metabolism Center, Durham, NC, 2009
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